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993 posts on clinical medicine, epidemiology, research methodology, statistics and code — in English and Thai. Filter by category and language, or search.
Non-Occlusive Mesenteric Ischemia (NOMI): Diagnosis, ICU Management, and Clinical Pitfalls
Introduction Non-occlusive mesenteric ischemia, or NOMI, is a life-threatening form of acute mesenteric ischemia in which the bowel becomes ischemic without an obstructing thrombus or embolus in the mesenteric vessels. The core problem is low intestinal blood flow, usually from shock, severe cardiac dysfunction, hypovolemia, sepsis, or excessive vasoconstriction from vasopressors. The World Society of Emergency Surgery describes NOMI as a condition commonly caused by superior mesenteric...
Vibrio cholerae (Cholera): Pathophysiology, Diagnosis, and WHO-Recommended Treatment
✅ First-line (WHO / CDC guidelines) 1. Doxycycline (preferred in adults) Doxycycline (300 mg), single dose, po ✔️ First-line in adults ✔️ Reduces duration of diarrhea and bacterial shedding 2. Azithromycin (preferred in children & pregnant women) Azithromycin (1 g), single dose, po (adult) Children: 20 mg/kg single dose ✔️ Safe in pregnancy ✔️ Good for areas with tetracycline resistance 3. Ciprofloxacin (alternative) Ciprofloxacin (1 g), single dose, po OR Ciprofloxacin (500 mg), 1×2 po, for...