Introduction Missing data is an inevitable reality in clinical research. From incomplete medical records to patient dropouts in follow-up...

Introduction Regression analysis is foundational in clinical research, serving as a tool to examine and quantify relationships between...

🧾 Comprehensive Rabies PEP Decision Table (with Vaccine and RIG Schedule) Category Immune Status Vaccination History Management Vaccine Schedule (Day) RIG Required CAT 1 All Any ❌ No treatment – ❌ No CAT 2 Normal Vaccinated (within 6 months) Booster Day 0 (1 dose IM or ID) ❌ No CAT 2 Normal Vaccinated (>6 months) Booster IM Day 0, 3 or ID Day 0, 3 or ID 4-site Day 0 ❌ No CAT 2 Normal Never vaccinated Full vaccine IM Day 0, 3, 7, 14, 28 or ID 2-site Day 0, 3, 7, 28 ❌ No CAT 2

🔍 Clinical Context: PCP in HIV/AIDS Patients Epidemiology and Pathogenesis Pneumocystis jirovecii  is a fungal pathogen causing...

Introduction Platelets play a vital role in primary hemostasis, and thrombocytopenia (low platelet count) increases the risk of...

🩺 Amiodarone IV Management Overview 1. Indication Stable or unstable ventricular tachycardia (VT) Ventricular fibrillation (VF)...

Overview In cases of Dengue fever , particularly in moderate to severe dengue , managing menstruation can be clinically significant due...

Overview Primolut N (Norethisterone)  and Provera (Medroxyprogesterone acetate)  are synthetic progestins  used in managing a variety of...

1. What Is a Seizure? A seizure  is a transient, uncontrolled electrical discharge of neurons  in the brain, causing altered behavior,...

Introduction In the age of personalized medicine, there is increasing recognition that population-level evidence may not always translate...

Introduction Crossover trials represent a specialized type of randomized controlled trial (RCT) used in clinical research to compare two...

🧠 Core Objective: What is Δ? Δ represents the maximum allowable difference in effectiveness  between the new treatment and the standard,...

Introduction In clinical research, especially when effective therapies already exist, demonstrating that a new intervention is not...

1. Anemia in Lymphoma: Mechanisms and Clinical Insight Lymphoma, a malignancy of the lymphatic system, can lead to anemia through several...

Introduction Randomized controlled trials (RCTs) are designed to eliminate confounding through random assignment, making treatment groups...

🧪 Modified Intention-to-Treat (mITT): Cleaning for Convenience, at a Cost 🎯 What It Really  Estimates mITT estimates the effect of...

Introduction Randomized controlled trials (RCTs) are the gold standard for causal inference in clinical medicine, offering unparalleled...

Introduction Clinical trials are pivotal in shaping the evidence base of medicine. However, the interpretation of their results is deeply...

🔍 Introduction Clinical trials are the cornerstone of therapeutic evidence, yet the way data are analyzed often determines what the...

Stage of Analysis Stata Command(s) Import & Manage Data use, import excel, label variable, gen, drop, recode Explore Structure / Counts...

Introduction Randomized Controlled Trials (RCTs) are the gold standard in clinical research, designed to generate unbiased estimates of...

Introduction The purpose of a clinical trial is not just to generate numbers, but to provide meaningful, interpretable answers  to...

Introduction Navigating a therapeutic clinical study isn’t just about reading results—it's about reverse-engineering the trial’s logic,...

🧪 Table: Blinding Tiers in Clinical Trials – Who, Why, and How Blinding Tier Blinded Role Why It Matters Example Scenario Single-Blind...