Choosing the Right Regression Model: A Visual Guide for Outcome Types in Clinical Research
- Mayta
- Jun 23
- 2 min read
In clinical epidemiology and biostatistics, choosing the correct regression model hinges on the characteristics of the outcome variable YY. The table below aligns outcome types with the appropriate regression model, the mathematical behavior of the model, the assumed statistical distribution, and an intuitive memory aid to support learning:
Table: Mapping Outcome Types to Regression Models
Model | Nature of Y | Mathematical Shape | Distribution | Memory Aid |
Linear (regress) | Continuous | Straight Line | Normal | Floating mean values |
Logistic (logistic) | Binary | Sigmoid Curve | Binomial | Curves between 0–1 |
Poisson (poisson) | Count/Event | Log-linear (exponential) | Poisson | More count → steeper rise |
Cox (stcox) | Time-to-event | Survival Step-curve | Time-to-event | Survival in steps |
Narrative Summary
Each model corresponds not only to a different statistical function but also to a fundamentally distinct mathematical and visual interpretation:
Linear Regression (regress)
Y: Continuous variable (e.g., blood pressure)
Graph: A straight line through data points; models mean change
Distribution: Assumes normally distributed errors
Use Case: Estimating the change in means across groups or continuous predictors
Logistic Regression (logistic)
Y: Binary outcome (e.g., alive vs. dead)
Graph: S-shaped sigmoid curve; models probability
Distribution: Binomial distribution with a logit link
Use Case: Estimating odds ratios; constrained between 0–1
Poisson Regression (poisson)
Y: Count outcome (e.g., number of infections)
Graph: Exponential curve (linear in log scale)
Distribution: Poisson
Use Case: Modeling incidence rates or event frequencies
Cox Proportional Hazards Model (stcox)
Y: Time until an event (e.g., time to death)
Graph: Stepwise survival function or cumulative hazard curve
Distribution: Semi-parametric (no baseline hazard assumption)
Use Case: Estimating hazard ratios for time-to-event data
This framework simplifies the learning process for graduate students and researchers in clinical statistics, providing a clear link between outcome type, appropriate model, and its visual-mathematical rationale.
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