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Choosing the Right Regression Model: A Visual Guide for Outcome Types in Clinical Research

In clinical epidemiology and biostatistics, choosing the correct regression model hinges on the characteristics of the outcome variable YY. The table below aligns outcome types with the appropriate regression model, the mathematical behavior of the model, the assumed statistical distribution, and an intuitive memory aid to support learning:

Table: Mapping Outcome Types to Regression Models

Model

Nature of Y

Mathematical Shape

Distribution

Memory Aid

Linear (regress)

Continuous

Straight Line

Normal

Floating mean values

Logistic (logistic)

Binary

Sigmoid Curve

Binomial

Curves between 0–1

Poisson (poisson)

Count/Event

Log-linear (exponential)

Poisson

More count → steeper rise

Cox (stcox)

Time-to-event

Survival Step-curve

Time-to-event

Survival in steps


Narrative Summary

Each model corresponds not only to a different statistical function but also to a fundamentally distinct mathematical and visual interpretation:

  1. Linear Regression (regress)

    • Y: Continuous variable (e.g., blood pressure)

    • Graph: A straight line through data points; models mean change

    • Distribution: Assumes normally distributed errors

    • Use Case: Estimating the change in means across groups or continuous predictors

  2. Logistic Regression (logistic)

    • Y: Binary outcome (e.g., alive vs. dead)

    • Graph: S-shaped sigmoid curve; models probability

    • Distribution: Binomial distribution with a logit link

    • Use Case: Estimating odds ratios; constrained between 0–1

  3. Poisson Regression (poisson)

    • Y: Count outcome (e.g., number of infections)

    • Graph: Exponential curve (linear in log scale)

    • Distribution: Poisson

    • Use Case: Modeling incidence rates or event frequencies

  4. Cox Proportional Hazards Model (stcox)

    • Y: Time until an event (e.g., time to death)

    • Graph: Stepwise survival function or cumulative hazard curve

    • Distribution: Semi-parametric (no baseline hazard assumption)

    • Use Case: Estimating hazard ratios for time-to-event data

This framework simplifies the learning process for graduate students and researchers in clinical statistics, providing a clear link between outcome type, appropriate model, and its visual-mathematical rationale.

Let me know if you'd like this converted to a formatted PDF or Word document for inclusion in your coursework.

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