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Understanding the differences between AKI, AKD, and CKD: A Comprehensive Guide.

Updated: Jan 22

Before diagnosing Acute Kidney Injury (AKI), Acute Kidney Disease (AKD), or Chronic Kidney Disease (CKD) based on rising creatinine levels, it's crucial to consider Pseudoazotemia. The cause may be gastrointestinal bleeding elevation, medications, increased protein intake, and muscle mass.


AKI, AKD, and CKD timelines:


In summary:

  • AKI: Rapid onset, within 0-7 days, with a sudden decrease in kidney function.

  • AKD: Kidney dysfunction or damage lasting less than 3 months.

  • CKD: Persistent decline in kidney function or damage for more than 3 months.

Key Differences:

  • AKI: Sudden onset, potentially reversible, primarily focused on identifying and treating the underlying cause.

  • AKD: Transitional phase between AKI and CKD, requires careful monitoring to assess recovery or progression.

  • CKD: Chronic and usually progressive, management focused on slowing progression and treating complications.



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